What Is Over-the-counter Insulin?

PRESS RELEASE
Published August 29, 2024

Over-the-counter (OTC) insulin is a type of insulin that can be purchased without a prescription. Unlike prescription insulin, which requires a doctor’s approval and supervision, OTC insulin is accessible directly from pharmacies or online retailers. OTC insulin is typically older formulations, such as regular insulin (short-acting) and NPH insulin (intermediate-acting), that have been used for many years to manage blood sugar levels in people with diabetes. Understanding OTC insulin options is crucial for those who may need insulin quickly or cannot access prescription insulin due to financial constraints or other barriers.

In this article, you will learn about the different types of OTC insulin, how they work, where to buy them, their benefits and risks, and important considerations before making the switch.

What Are the Different Types of Over-the-counter Insulin?

There are two main types of over-the-counter insulin available: Regular insulin and NPH insulin.

  • Regular Insulin: This is a short-acting insulin that begins to work within 30 minutes of injection, peaks around 2-4 hours, and lasts for about 6-8 hours. It is typically used before meals to control blood sugar spikes caused by eating.
  • NPH Insulin: This intermediate-acting insulin begins to work about 1-2 hours after injection, peaks around 4-12 hours, and can last up to 18 hours. It is often used to provide basal (background) insulin coverage throughout the day or overnight.

OTC insulin differs from prescription insulin in several ways. Prescription insulin includes more modern formulations, such as rapid-acting, long-acting, and ultra-long-acting insulins, which offer more precise blood sugar control and flexibility. These newer insulins are designed to closely mimic the body’s natural insulin response and have fewer peaks and troughs compared to OTC options. While OTC insulin can be effective for some individuals, it may not provide the same level of control as newer prescription insulins.

How Does Over-the-counter Insulin Work?

Over-the-counter insulin works by helping to lower blood sugar levels in people with diabetes. When you inject insulin, it helps glucose (sugar) from the blood enter your cells, where it is used for energy. In people with diabetes, the body either does not produce enough insulin (as in type 1 diabetes) or does not respond to insulin properly (as in type 2 diabetes). By injecting insulin, you help your body manage blood sugar levels, preventing complications from high blood sugar.

One of the OTC options is regular insulin, which starts working relatively quickly and is used to control blood sugar spikes after meals. NPH insulin, on the other hand, provides longer-lasting blood sugar control and is typically used to manage blood sugar levels throughout the day or night.

Compared to prescription insulins, OTC insulin may be less effective in providing smooth and consistent blood sugar control. Prescription insulins, such as long-acting or rapid-acting formulations, are designed to better mimic the body’s natural insulin release, reducing the risk of blood sugar fluctuations. However, OTC insulin can still be an important tool for those who need immediate access to insulin without the barriers of obtaining a prescription.

What Are the Benefits of Using Over-the-counter Insulin?

Over-the-counter insulin offers several benefits, particularly for individuals who need immediate access to insulin without the need for a prescription. One of the primary reasons someone might choose OTC insulin is its availability; it can be purchased directly from pharmacies or online without a doctor's prescription. This can be especially beneficial for people who cannot afford the high cost of prescription insulin or those who have limited access to healthcare providers.

Another benefit is the affordability of OTC insulin compared to some of the newer, prescription-only insulins. While it may not offer the same level of control as modern insulins, OTC insulin is often significantly cheaper, making it a viable option for people who are uninsured or underinsured.

However, there are also cons to consider. OTC insulin is typically older formulations, such as regular insulin and NPH insulin, which may not provide the same flexibility and precision in blood sugar management as newer insulins. These older insulins have more pronounced peaks and troughs, which can make blood sugar levels harder to control. In contrast, prescription insulins, like rapid-acting or long-acting options, offer smoother and more predictable blood sugar control, which can be crucial for avoiding complications.

Are There Any Risks Associated With Over-the-counter Insulin?

Using over-the-counter insulin carries several potential risks, primarily due to the older formulations it includes. Regular and NPH insulins, the two main types of OTC insulin, have a higher risk of causing blood sugar fluctuations compared to newer, prescription insulins. These fluctuations can lead to hypoglycemia (low blood sugar) if the insulin peaks too strongly or hyperglycemia (high blood sugar) if the insulin wears off too quickly.

One of the major risks is the potential for incorrect dosing. OTC insulins require more careful timing and dose adjustments, and without proper guidance from a healthcare provider, there is a higher chance of administering too much or too little insulin. This can lead to severe hypoglycemia, which can be life-threatening if not treated promptly.

To mitigate these risks, it's essential to carefully follow the instructions on dosing and timing. Monitoring blood sugar levels frequently is also critical when using OTC insulin, as it helps in making necessary adjustments to avoid extreme highs or lows. For those who are new to insulin or switching from prescription insulin to OTC options, consulting with a healthcare provider, even if just for initial guidance, can help minimize these risks.

How Much Does Over-the-counter Insulin Cost?

Over-the-counter insulin is generally more affordable than prescription insulin, making it an attractive option for those without insurance or those looking to reduce their out-of-pocket costs. The cost of OTC insulin typically ranges from $25 to $90 per vial, depending on the pharmacy and the type of insulin. This is significantly less expensive than many of the newer, prescription-only insulins, which can cost several hundred dollars per vial.

Prescription insulins, especially those that are newer and more advanced, such as long-acting and rapid-acting insulins, tend to be more costly. Prices for these insulins can range from $300 to $600 or more per vial without insurance. Even with insurance, the co-pays for prescription insulins can be high, particularly if a person is using multiple types of insulin or has a high deductible.

To save money when purchasing OTC insulin, consider buying it from large retail pharmacies, which often have lower prices compared to smaller, independent pharmacies. Some retailers also offer discount programs or membership savings that can further reduce the cost. Additionally, purchasing in bulk or using coupons available through pharmacy discount cards can help lower the overall expense.

While OTC insulin is more cost-effective, it’s important to weigh this against the need for effective blood sugar management, as the savings may not always be worth the potential risks associated with older insulin formulations.

Where Can You Buy Over-the-counter Insulin?

Over-the-counter (OTC) insulin can be purchased at various locations, including local pharmacies, big-box retail stores, and online retailers. Some of the most common places to buy OTC insulin include:

  • Pharmacies: Many major pharmacy chains, such as Walmart, CVS, and Walgreens, carry over-the-counter insulin, including brands like Novolin R and Humulin R. These insulins are usually available in the diabetes care section or can be requested from the pharmacy counter.
  • Big-Box Retail Stores: Stores like Walmart often have a pharmacy section where you can purchase OTC insulin. Walmart's ReliOn brand offers Novolin R at a lower cost compared to other brands, making it a popular option for those looking to save money.
  • Online Retailers: You can also buy over-the-counter insulin online from reputable retailers. For example, BuyCanadianInsulin.com offers Novolin R and Humulin R at competitive prices, often lower than what you might find in US pharmacies. This can be a convenient option for those who prefer to order insulin from home and have it delivered.

Can Over-the-counter Insulin Be Used for All Types of Diabetes?

Over-the-counter insulin can be used to manage certain types of diabetes, but it is not suitable for all cases. OTC insulin, which primarily includes regular insulin and NPH insulin, can be effective in managing blood sugar levels in individuals with type 1 diabetes and some people with type 2 diabetes.

For type 1 diabetes, where the body produces little or no insulin, OTC insulin can be used to manage blood sugar levels, but it requires careful monitoring and precise dosing. Because OTC insulin formulations are older, they may not provide the same level of control as newer, prescription insulins, which are designed to closely mimic natural insulin release. This can make blood sugar management more challenging for people with type 1 diabetes who need consistent and reliable insulin coverage.

For type 2 diabetes, which is characterized by insulin resistance or insufficient insulin production, OTC insulin may be used when other treatments, such as oral medications, are no longer effective. However, type 2 diabetes often requires a combination of insulin and other medications to manage effectively, and OTC insulin alone may not be sufficient for all patients.

It’s important to note that OTC insulin may not be appropriate for people with gestational diabetes (diabetes during pregnancy) or for those with very high insulin needs. Its limitations, including its less predictable blood sugar control and the need for precise timing and dosing, make it less suitable for these cases.

What Should You Consider Before Switching to Over-the-counter Insulin?

Before switching to over-the-counter insulin, several important factors must be considered. First and foremost, it's crucial to understand the differences between OTC and prescription insulin. OTC insulins, such as regular and NPH insulin, are older formulations with different action profiles compared to newer insulins. They may not provide the same level of control over blood sugar levels, which can increase the risk of hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar).

Another key consideration is the dosing and timing of OTC insulin. Because these insulins have more pronounced peaks and shorter durations, they require careful timing around meals and more frequent blood sugar monitoring. If you are accustomed to using long-acting or rapid-acting insulins, switching to OTC options may involve significant changes in your diabetes management routine.

It's also essential to consider the availability of support and guidance. While OTC insulin is more accessible, it is still important to have a healthcare provider’s input when making the switch. Consulting with a healthcare provider can help ensure that you are using the correct dosage and timing and that you are monitoring your blood sugar levels appropriately. Even though OTC insulin is available without a prescription, managing diabetes effectively requires a solid understanding of how insulin works and how it interacts with your body.

Lastly, think about the cost implications. While OTC insulin is less expensive, it’s important to balance the cost savings with the potential need for more frequent blood sugar testing and adjustments to your insulin regimen. The savings may not be as significant if you find that you need additional tools or medications to manage your blood sugar effectively.

Conclusion

Over-the-counter insulin offers a more accessible and affordable option for managing diabetes, particularly for those who may face barriers in accessing prescription insulin. OTC insulin can be effective for some people with type 1 or type 2 diabetes, but it comes with limitations, including less predictable blood sugar control and the need for careful dosing and timing.

Before making the switch to OTC insulin, it’s essential to weigh the pros and cons, considering factors such as the type of diabetes you have, your current insulin regimen, and the potential risks involved. Consulting with a healthcare provider, even when using OTC insulin, is advisable to ensure that you manage your diabetes safely and effectively. While OTC insulin can be a valuable tool, it is important to approach its use with caution and a clear understanding of its limitations in diabetes management.

FAQs About Over-the-Counter Insulin

Can I buy over-the-counter insulin online?

Yes, over-the-counter insulin can be purchased online from various pharmacies and retailers. It's important to buy from reputable sources to ensure the insulin is stored and handled correctly.

Is over-the-counter insulin safe?

Over-the-counter insulin is generally safe when used correctly, but it requires careful dosing and timing. Since it is an older type of insulin, it may not offer the same level of blood sugar control as newer prescription insulins.

How should over-the-counter insulin be stored?

Over-the-counter insulin should be stored in the refrigerator before opening. Once opened, it can be kept at room temperature for up to 28 days, depending on the manufacturer’s instructions. It should not be exposed to extreme temperatures.

Can over-the-counter insulin be used in an insulin pump?

Over-the-counter insulin is generally not recommended for use in insulin pumps because it may not provide the precise and consistent delivery required for pump therapy. Insulin pumps are typically used with rapid-acting prescription insulins.

Is over-the-counter insulin the same as human insulin?

Yes, over-the-counter insulin, such as regular and NPH insulin, is human insulin. It is identical to the insulin produced by the human pancreas, though it may not act as quickly or last as long as some newer analog insulins.

What happens if I inject too much over-the-counter insulin?

Injecting too much over-the-counter insulin can cause hypoglycemia (low blood sugar), which can be dangerous. Symptoms include shakiness, sweating, dizziness, and confusion. It's important to monitor your blood sugar levels and have a source of fast-acting sugar on hand.

How do I know which over-the-counter insulin to use?

The type of over-the-counter insulin you use depends on your specific needs, such as how your body responds to insulin and your blood sugar patterns. Regular insulin is typically used before meals, while NPH insulin is used for longer-lasting control.

Can I mix regular insulin and NPH insulin?

Yes, regular insulin and NPH insulin can be mixed in the same syringe. Regular insulin should be drawn into the syringe first, followed by NPH insulin. Mixing them allows for a combination of short- and intermediate-acting effects.

Can children use over-the-counter insulin?

Over-the-counter insulin can be used in children with diabetes, but it requires careful monitoring of blood sugar levels and precise dosing. It's important to use the insulin as directed and monitor the child’s blood sugar closely.

What should I do if I miss a dose of over-the-counter insulin?

If you miss a dose of over-the-counter insulin, check your blood sugar levels and follow your regular insulin schedule. Do not double up on your next dose to make up for the missed one.

Can over-the-counter insulin be used for gestational diabetes?

Over-the-counter insulin may be used for gestational diabetes, but it requires careful monitoring and control. The specific type of insulin and dosage will depend on individual blood sugar patterns.

Are there any side effects of over-the-counter insulin?

Common side effects of over-the-counter insulin include hypoglycemia (low blood sugar), injection site reactions (such as redness or swelling), and, less commonly, allergic reactions. Monitoring and proper injection techniques can help minimize side effects.

Can over-the-counter insulin cause weight gain?

Like other types of insulin, over-the-counter insulin can cause weight gain. This is because insulin helps the body store glucose, which can lead to an increase in fat storage if more calories are consumed than burned.

Does over-the-counter insulin work as well as prescription insulin?

Over-the-counter insulin can be effective in managing blood sugar levels, but it may not work as precisely as newer prescription insulins. The choice between OTC and prescription insulin depends on individual needs, preferences, and circumstances.

Vehement Media