DelveInsight’s “Myelodysplastic Syndrome Market” report provides a thorough comprehension of the Myelodysplastic Syndrome historical and forecasted epidemiology and the Myelodysplastic Syndrome market trends in the 7MM [the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan]. The Myelodysplastic Syndrome market report also proffers an analysis of the current Myelodysplastic Syndrome treatment algorithm/practice, market drivers, market barriers, and unmet medical needs.
The Myelodysplastic Syndrome market is expected to show positive growth, mainly attributed to the increased diagnosed prevalence and also, the launch of upcoming devices during the forecast period. Moreover, advances in disease mechanisms have yielded new diagnostic and treatment approaches, opening avenues to better treatment interventions.
Key Takeaways from the Myelodysplastic Syndrome Market Research Report
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Myelodysplastic Syndrome Overview
Myelodysplastic Syndrome is a heterogeneous group of hematologic neoplasms classically described as a clonal disorder of hematopoietic stem cells leading to dysplasia and ineffective hematopoiesis in the bone marrow.
Myelodysplastic Syndrome Epidemiology Segmentation in the 7MM
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Myelodysplastic Syndrome Treatment Market
The current Myelodysplastic Syndrome treatment landscape for patients comprises allo-HSCT, non-intensive therapies ranging from iron chelation and growth factors to lenalidomide and HMA. Allo-HSCT remains the only curative for this patient pool. Other approaches are non-curative, improving quality of life, and delaying disease progression.
Myelodysplastic Syndrome Therapies
Other than these current therapies, the Myelodysplastic Syndrome pipeline is robust and possesses multiple potential drugs in the late, mid, and early stages of developments, yet to be launched. The emerging pipeline of MDS possesses several potential products developed in different stages of clinical development. The expected launch of potential therapies, namely FibroGen (roxadustat), AbbVie (Venclexta ± azacitidine), Novartis (sabatolimab), Syros Pharmaceuticals (SY-1425 + azacitidine), Gilead Sciences (magrolimab ± azacitidine), Geron Corporation (imetelstat), Takeda (pevonedistat ± azacitidine), Pfizer (glasdegib + azacitidine), Aprea Therapeutics (eprenetapopt), Jazz Pharmaceuticals (CPX-351), Karyopharm Therapeutics (eltanexor), BerGenBio (bemcentinib), Bristol Myers Squibb (enasidenib), Sanofi (fludarabine + busulfan ± clofarabine and Medac (treosulfan ± fludarabine) may increase Myelodysplastic Syndrome market size in the coming years, assisted by an increase in the MDS patient pool.
Learn more about the Myelodysplastic Syndrome therapies in clinical trials @ Myelodysplastic Syndrome Ongoing Clinical Trials Analysis
Myelodysplastic Syndrome Market Analysis
Myelodysplastic Syndrome market to growing due to the current MDS treatment options that include curative, supportive, and symptomatic treatments, which are easily and widely available in the market, and their generics. Moreover, various studies have highlighted the role of multiple gene mutations like RUNX1, TP53, TET2, DNMT3A, ASXL1, and others in MDS. The emerging therapies such as Syros Pharma’s SY-1425 and BMS’ Enasidenib are being developed as targeted therapies for RARA positive and IDH-2 mutated patients, respectively. The companies are developing therapies with targetable mutations that will open a new window of opportunity for companies developing MDS therapies.
Myelodysplastic Syndrome Market Growth
However, the growth of the Myelodysplastic Syndrome market will be hampered by the lack of the latest evidence and analysis related to drug prescription pattern share for Myelodysplastic Syndrome patients in EU5 countries. Also, the disease affects old age people, and most of these patients are ineligible for HSCT, which is currently the only curative option. Some MDS patients undergoing treatment with HMA might fail the therapy, due to which they might not have many treatment options left. In addition to that, the upcoming therapies might face some competition from the approved and established therapies for MDS and the various upcoming therapies in the Myelodysplastic Syndrome pipeline. The high-cost burden for the overall Myelodysplastic Syndrome treatment might threaten the current MDS market.
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Scope of the Myelodysplastic Syndrome Market Insight Report
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Table of content
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