India Human Microbiome Market Introduction
Trillions of microbes, or bacteria, live in the human body. Most of these are beneficial, but can be harmful when out of balance. The terms microbiota and microbiome are used interchangeably. Microbiota is a diverse community of bacteria, viruses, fungi, and other microorganisms found in a specific environment such as the human digestive tract. Human biome refers to the body’s entire habitat that includes microorganisms, genomes, and environmental conditions.
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Prevotella, Ruminococcus, Bacteroides, and Firmicutes are large families of bacteria found in human gut microbiome. Peptostreptococcus, Bifidobacterium, Lactobacillus, and Clostridium are anaerobic bacteria found in the colon, which have low oxygen levels. These microbes prevent uncontrolled growth of harmful bacteria, as they compete for nutrients and attachment sites on mucus membranes of the gut – a major site of immune activity and antimicrobial protein production.
According to the India human microbiome market analysis, the probiotic industry in the country is growing at a steady pace and has the potential to advance at a rapid pace in the near future. The industry has been expanding after the introduction of various pharmaceutical probiotic formulations in the market. Incidence of chronic diseases such as diabetes, non-alcoholic fatty liver disease, coronary artery disease, numerous chronic inflammatory disorders with an immune basis, and some types of cancer is on the rise in India due to the sedentary lifestyle of the people.
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Increase in Proactive Research on Human Gut Microbiota in India
India provides a unique scenario for human microbiome research. Anthropologists and geneticists have been fascinated for decades by the enormous diversity in genetic composition, dietary habits, and ethnicity in India. Studies of human gut microbiome in the Indian population would help understand how the gut microbiome changes in the presence of various diseases and the potential effects these changes may have on human health. Additionally, R&D in human gut microbiome is likely to reveal novel information about various topics such as genetics, cultural affinities, dietary practices, and changing lifestyles.
The Government of India has taken initiatives to develop research studies on human microbiome diseases. The Human Microbiome Project (HMP) is a joint effort of public and private research institutes and universities across the country, including the All India Institute of Medical Sciences in New Delhi, the Institute of Advanced Study in Science and Technology in Guwahati, and Symbiosis International University in Pune. The National Centre for Microbial Resource (NCMR) in Pune, a part of National Centre for Cell Science, is leading the research.
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Rise in Demand for Probiotic Products to Drive India Human Microbiome Market
In terms of product & services, the product segment held significant share of the India human microbiome market in 2021. The segment has been split into prebiotics, probiotics, drugs, and others. Increase in demand for probiotic products is expected to fuel the India human microbiome market size during the forecast period. Rise in number of working women and increase in emphasis on improving women’s health are also propelling the adoption of specialized probiotics such as Lactobacillus acidophilus, Lactobacillus rhamnosus, and Bifidobacterium.
Surge in demand for probiotic curd, yogurt, and drinks in convenient, portable, and flexible packaging materials is expected to fuel the India human microbiome market during the forecast period. Consumption of probiotic food products in India has been increasing, as many people are preferring healthy food alternatives.
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High Prevalence of Gastrointestinal Ailments to Augment Gastrointestinal Disorders Segment
The gastrointestinal disorders segment accounted for the largest India human microbiome market share in 2021. Growth of the segment can be ascribed to the high prevalence of various gastrointestinal ailments and increase in awareness about these ailments. Clostridioides difficile (C. difficile) is a major nosocomial pathogen that infects human gastrointestinal tract and causes diarrhea. Antibiotics treatment, which disrupts the normal gut microbiota, is a major risk factor. Human gut microbiome plays a vital role in the Clostridium Difficile infection treatment. Lactobacillus-based probiotics are used to prevent the onset of Antibiotic-associated Diarrhea (AAD) and C. difficile infection in humans.
Probiotics improve gut health and boost immunity. The geriatric population is more prone to chronic gastrointestinal disorders. Thus, increase in geriatric population and the subsequent demand for probiotics is driving the gastrointestinal disorders segment. Demand for microbiome is propelled by a shift in preference of consumers from a high-calorie diet to functional foods and beverages. Additionally, there is significant increase in burden of gastrointestinal (GI) and liver diseases along with gut microbiome studies in India. These factors are also likely to drive the gastrointestinal disorders segment during the forecast period.
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Analysis of Key Players in India Human Microbiome Market
The India human microbiome market is consolidated, with the presence of a small number of leading players. Expansion of product portfolio and mergers and acquisitions are key strategies adopted by leading players in the market. Unique Biotech, OptiBiotix Health Plc., Tata Chemicals Ltd., Bione, Illumina, Inc., Charles River Laboratories, QIAGEN, and Allianz Biosciences Pvt. Ltd. (ABPL) are prominent players operating in the India human microbiome market.
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