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article imageAnother batch of GM monkeys born

By Tim Sandle     Feb 22, 2014 in Science
More monkeys with edited genomes have been born in a research lab. Scientists hope that the genetic editing techniques can one day be used to eliminate genetic diseases in people.
It has been reported that a female cynomolgus monkey was born with mutations made to her genes. For this, the scientists behind the birth used a novel gene-editing technique on the embryo while it was still in the mother.
This is the second "genetically modified" monkey to be born. Earlier this month Digital Journal reported that twin monkeys have been born, but not in the conventional sense. These are the first primates born whose genomes were edited using a novel CRISPR technology (a type of genome editing).
With the new monkey, a different gene editing method was use called transcription activator-like effector nucleases (TALENs). This allows for targeted mutagenesis. That is, a process where other genes can be added and these added genes can affect the development and characteristics of the monkey.
The findings in relation to the cynomolgus monkey have been published in the journal Cell: Stem Cell. The paper is titled "TALEN-Mediated Gene Mutagenesis in Rhesus and Cynomolgus Monkeys."
The long-term aims are to try the different techniques with human cells, as a way to avoid people being born with certain genetic diseases.
More about Monkeys, Genetically modified, Genes, Gmo
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