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Killing cancer by exploding tumor cells

By Tim Sandle     Mar 29, 2014 in World
Atlanta - Scientists have heralded a new drug tested in mice, which causes tumor cells to explode, as a major breakthrough. The drug has been tested out on mice.
The new drug is called Vacquinol-1. Studies have shown that the drig causes cancer cells to burst open. This seemingly represents a entirely new mechanism of killing cancer.
In studies, according to The Verge, the drug prompted cells to over-develop vacuoles, become perfectly round, break apart, and die. Moving onto animal models, the scientists showed that mice with glioblastoma—a form of brain cancer in humans—that were given Vacquinol-1 orally for five days ended up with either smaller tumors than control mice or no tumors at all.
Commenting further, Patrik Ernfors, a coauthor of the study and a researcher at the Karolinska Institute, said in a press release: "We now want to try to take this discovery in basic research through preclinical development and all the way to the clinic. The goal is to get into a phase 1 trial."
The study was led by Ravi Bellamkonda, a neuroscientist at the Georgia Institute of Technology. The research has been published in the journal Cell. The paper is titled "Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule."
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