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Gut bacteria linked to Crohn's Disease

By Tim Sandle     Mar 15, 2014 in Health
A new study has found that the gut microbiomes of patients with Crohn’s disease are markedly different than those of healthy individuals.
The finding suggests that the development of Crohn’s disease may be marked by changes in the balance of bacteria in the gut. Crohn's disease is a type of inflammatory bowel disease that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea (which may be bloody if inflammation is severe), vomiting, or weight loss.
This follows on from an earlier Digital Journal report which discussed new evidence that showed that IBS is associated with an imbalanced composition of the gut microbiota.
To reach the conclusion, the researchers examined fecal samples and took intestinal and rectal biopsies from almost 670 children and adolescents with and without the disease. Lead researcher Ramnik Xavier of Massachusetts General Hospital and Harvard Medical School told ABC that "“There is an increase in the so-called inflammation-associated bacteria and there is a decrease in bacteria that are good for health."
According to Science News, the scientists also found that antibiotic use amplified the imbalance. The study confirmed that antibiotics do not do any good to people with Crohn’s disease.
The new findings have been published in the journal Cell Host & Microbe. The paper is titled "The Treatment-Naive Microbiome in New-Onset Crohn’s Disease."
More about Crohn's Disease, Bacteria, Gut, gut microbes, microflora
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