Scientists have found new genetic markers that could be used to help diagnose and combat a type of brain tumour that mainly targets children.
An international collaboration between the University of Nottingham and the Hospital for Sick Kids in Toronto has studied the causes of central nervous system primitive neuroectodermal brain tumours, a disease for which prognoses are typically extremely poor.
It was found that these tumours have three sub-types featuring distinct genetic abnormalities, leading to different outcomes for patients, with each group having its own genetic signature through differences in the expression of LIN28 and OLIG2.
Using these markers, clinicians could diagnose and predict outcomes for young patients more accurately in future.
For further details, see Sick Kids.