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Clinical trial to test effects of coconut oil against Alzheimer’s

By E. Hector Corsi     Nov 8, 2013 in Health
New research suggests that coconut oil may help fight Alzheimer’s disease (AD), and a clinical trial will be conducted to test its effects against AD.
One of the main causes of AD is amyloid-β (Aβ) peptide. A new in-vitro study shows that coconut oil can reduce the toxic effects of amyloid-β (Aβ) peptide on neurons. Firoozeh Nafar and Karen M. Mearow of Memorial University of Newfoundland showed that coconut oil can improve the survival of neurons affected by Aβ. Their study will be published in an upcoming issue of the Journal of Alzheimer’s Disease.
Coconut oil has a high content of medium chain triglycerides (MCT), and these fats have shown benefits in a recent clinical trial on humans with AD, where a special formulation of the fats was used.
MCTs have shown benefits in animal subjects, such as reductions in Aβ precursor protein and Aβ levels.
A new clinical trial on humans will examine the effects of a blend of coconut and medium chain triglyceride oils on AD. The study will be conducted by Amanda G. Smith, MD , the principal investigator, and her colleagues at the University of South Florida (USF) Health Byrd Alzheimer's Institute in Tampa, Florida.
Although coconut oil may eventually be shown to help patients with AD, it is important to conduct more research. The fats from coconut oil do seem to have plausible mechanisms of actions against AD, such as producing ketones, which provide energy to neurons, and they lower toxic proteins implicated in AD. If you decide to use coconut oil or MCTs, which are widely available, be aware that MCTs may cause diarrhea. You should slowly increase your dosage, from one teaspoon per day to about two to four tablespoons per day. Purchase only non-hydrogenated coconut oil, or MCT oil with no additives, and always advise your doctor if you plan to use these products.
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