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article imageDevelopments in personalized cancer therapy

By Tim Sandle     Oct 2, 2013 in Health
Scientists are developing individualized tumor treatment methods based on the genetic profile of different cancers. This would be an alternative to giving patients generalized medicines.
The idea behind the research is that if medications are designed to target individual patients based on their unique cancers then such medicines should be more effective than general anti-cancer drugs.
The research has been advanced by the data made available from The Cancer Genome Atlas (TCGA), funded by the US National Institutes of Health. This analysis has shown that from more than 3000 samples there are broadly 12 different tumor types. Of these, a limited number of specific genetic events appear to cause most tumor subtypes and tumors. By understanding more about these tumors then specialized medicines can be developed.
The research was carried out by researchers at Memorial Sloan-Kettering Cancer Center and it has been published in Nature Genetics. The paper is titled “Emerging landscape of oncogenic signatures across human cancers.”
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