Remember meForgot password?
    Log in with Twitter

article imageSecrets of typhoid fever revealed

By Tim Sandle     Jul 14, 2013 in Science
Typhoid is one of the world's oldest and most deadly diseases. Until recently scientists have not fully understood why it is so potent. New research sheds some new light on the old killer.
Typhoid fever is a common worldwide bacterial disease transmitted by the ingestion of food or water contaminated with the feces of an infected person, which contain the bacterium Salmonella typhi.
Researchers based at Yale University have provided an explanation of how typhoid, a disease marked by delirium and stupor, still kills an estimated 200,000 people every year. In the U.S., it is estimated that approximately 5,700 cases occur annually.
The potency of the disease is due to a powerful toxin possessed by Salmonella typhi, the bacterium that causes typhoid fever.
The identification of the toxin has come from studies carried out in mice. The reason why the toxin has proved to be so hard to identify is because the typhoid toxin is created from the merger of two separate and powerful toxins. Once the mice showed a reaction, the toxin was identified through atomic analysis.
The report identifying the toxin has been published in the journal Nature in a paper titled "Structure and function of the Salmonella Typhi chimaeric A2B5 typhoid toxin."
More about Typhoid, Typhoid fever, Toxins, Fever, Bacteria
More news from
Latest News
Top News