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Teeth grown from mouse cells

By Owen Weldon     Mar 9, 2013 in Science
Researchers say that the possibility of growing new teeth on a patient's jaw is rising because of a hybrid of human gum cells and mouse stem cells.
According to Guardian, in the future people may be able to have diseased teeth or missing teeth replaced with ones that have been grown from cells that have been taken from their own mouth.
Scientists were able to grow hybrid teeth in a laboratory, and researchers are now hoping that the work could lead to dentures being superseded by hybrid teeth.
According to a study published in the Journal Of Dental Research, mouse and human cells were transplanted into the kidneys of an adult mouse. After a while, recognizable tooth structures, that were coated in enamel, as well as viable developing roots, grew.
According to Independent, the mouse cells were mesenchymal cells while the gum cells were epithelial cells. The gum cells formed the outer hard enamel of a tooth, while the mouse cells formed the inner dentine and tooth pulp.
However, the hybrid tooth cannot be used in human transplant dentistry because of the animal-derived material is in it. The tooth was only created to demonstrate that a viable tooth could be produced with the procedure.
The next step will be to identify a source of mesenchyna cells in a patient that could be combined with epithelial cells that could be used to make a pure-human immature tooth, which could be used to replace a lost tooth in a patient.
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