The crocodiles, according to a report by local daily Beeld, sprung from the Rakwena Crocodile Farm after the owners were forced to open the gates to ward off a storm surge.
At least 7,500 are still on the run after several had been rounded up.
"There used to be only a few crocodiles in the Limpopo River," Zane Langman, the son-in-law of Johan Boshoff, who owns Rakwena told
The Telegraph. "Now there are a lot."
Limpopo Province has been recently hit by floods that have reportedly killed 10 people displacing more.
the BBC, the South African Air Force is evacuating people affected by the flooding in remote regions.
The floods have also affected neighboring Mozambique, where thousands of people were being rescued from their homes.
Animal safety experts warned people
to stay indoors and stay away from the crocodiles, AFP reported.