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article imageAlzheimer's disease develops differently according to gender

By Tim Sandle     Nov 27, 2012 in Science
A new study from the U.S. has indicated that there are key differences in the way Alzheimer's disease develops between men and women.
Following from yesterday’s report in the Digital Journal about a potential therapy for Alzheimer's disease, comes a new research paper which suggests that there is a difference in the way that Alzheimer's disease develops between men and women.
With the research, PharmBiz notes, the scientists assessed a group of 109 patients of mixed gender over a period of five years (including 60 men and 49 women with a mean age of 77). During the five year period each subject progressed from mild cognitive impairment to full cases of Alzheimer's. By using magnetic resonance imaging, the researchers observed that women experienced greater atrophy in grey matter 12 months prior to and at the time of their Alzheimer's diagnosis than men.
However, as Eureka discusses, men subsequently saw a more aggressive development of the disease over a shorter period of time, with both the extent and distribution of grey matter loss.
This implies that the progression of Alzheimer’s disease is influenced by gender. The implications of the research may lead to the development of different drugs for men and women.
The research was undertaken at the Medical University of South Carolina and led by Dr. Maria Vittoria Spampinato.
More about Alzheimers, Alzheimer's disease, Gender, Male, Female
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