A joint effort between the University of Pittsburgh, University of California at Berkeley, and the Carnegie Mellon University produced a report published by Sleep
which shows that not only does poor sleep prevent vaccines from working, but overall immune response is also hindered greatly.
According to Scientific American
, 125 test subjects were all given the Hepetitis B vaccination in one, two, and six month intervals. During that time, they advised the volunteers to keep detailed records of their sleep habits.
Six months after the last vaccination, researchers then tested each volunteer's levels of antibodies against Hepatitis B. They found that 18 patients who had poor sleep schedules hadn't developed any antibodies. The study overall concluded that vaccines fail 12 times as often in people who get less than six hours of sleep.
The idea that sleep deprivation affects immunity is not new. A study
published in February 2009 linked T-cell production with the lack of sleep. T-cells
are the main white blood cells required to fight infection.