Psych Central report that
new research has discovered that the molecular structure of a protein that is involved in Alzheimer's disease and the amazing discovery that it binds cholesterol, could help bring about new treatments for the disease.
Charles Sanders. PhD, professor of biochemistry and investigators at Vanderbilt University reported in the June 1st issue of the Journal Science that amyloid-beta oligomers will eventually clot together and form plaques in the brain that are one of the signs of this disease. Anything that reduces production of amyloid-beta can help prevent or treat Alzheimer's disease.
This news could change the way Alzheimer's disease is treated in the future. They discovered that there was a binding domain in the protein. It has been thought for a long time, that cholesterol promotes the disease, but nobody was sure. The discovery points to a new way forward in treating Alzheimer's. The treatment would involve reducing amyloid-beta production.
A drug that could block cholesterol from binding to APP would help stop the protein going into lipid rafts. Medication that prevents beta or gama secretase to directly reduce amyloid beta production have been developed, but they have adverse side effects.
This new discovery of information is a scientific breakthrough and will change the lives of people all over the world. The research team at Vanderbilt combined medical knowledge and technological advancement to add the last piece of the puzzle.
Amyloid-beta clumps together into oligomers and destroys neurons. Once neurons are destroyed, dementia and memory loss occur. Alzheimer's is a disease that has killed many people all over the world. It is a disease, which leaves families and loved ones devastated. The results of Alzheimer's can take away someone's dignity and Independence. It can make the most placid person, aggressive. This news could change the lives of millions of people.