Those who were killed were between 17 and 19 years of age. Two died at the scene, near the Notre Dame Street and Place Turcot intersection, in southwest Montreal, while a third died after being taken to hospital.
Two others, in the same age range, were taken to hospital and treated for shock.
The accident took place around 3 a.m. on Sunday, in an area which is popular with graffiti artists.
Montreal police Constable Danny Richer said the men may have been in the area to spray graffiti on the interchange or on a Transport Quebec building, reported the
Montreal Gazette.
He said they may have not heard the train coming because the concrete structure of the interchange muffles sounds.
The train, which was arriving from Toronto, was about 10 kilometres from Central Station when the collision occurred. A bus took the approximately 45 passengers who had been on board to the station.