Research findings published in recent cancer journal have found that Bisphenol A (BPA), a chemical used in many common household items, cause normal breast cells to behave more like aggressive breast cancer cells.
A study published in Cancer Research, the journal from The American Association for Cancer Research, has found a connection between BPA and changes in normal, non-cancerous human breast cells, causing them to react more like aggressive breast cancer cells.
BPA is a controversial chemical that California is currently considering banning for children’s products and is found in everyday items such as plastic water bottles, baby bottles, dental sealants and even canned food linings.
California Pacific Medical Center Research Institute and Stanford Genome Technology Center performed study research on a few high-risk breast cancer participants by removing sample breast tissue of normal, non-cancerous breast cells. The cells were then exposed to BPA and analyzed for any activity.
According to study co-author and Principal Investigator, Shanaz Dairkee,
“We screened 40,000 genes in normal human cells that had been exposed to BPA and found a striking increase in the sets of genes that promote cell division, increase cell metabolism, and increase resistance to drugs that usually kill cancer cells, and prevent cells from developing to their normal mature forms,”
This study samples used were the closest to human flesh that researchers could ethically come by, making it as viable a study possible.
In animal studies, BPA has shown to have high rates of breast and prostate cancer, as well as serving as an immunosuppressant and causing male fertility issues due to low sperm counts.
In a study performed by the CDC, BPA was found to have a higher concentration in females than males in the blood and children had a higher concentration than adults. Concentrations of BPA in the amount used in the study have been found in the blood of pregnant women.
With both strong animal study evidence and CDC findings, the recent CPMCRI study results creates a definite reason to explore further testing in the area of BPA and its relation to breast cancer.
It also opens the door for other possibilities as far as other correlative indications.
Additional BPA Information